Dopamine - Dr. Anna Lembke - Neuroscience

Dopamine - Dr. Anna Lembke - Neuroscience

How to Balance Dopamine Levels in a World of Pleasure

Dopamine is at the core of how our brain experiences pleasure and reward, and in this episode, Dr. Anna Lembke, Chief of the Stanford Addiction Medicine Dual Diagnosis Clinic and author of Dopamine Nation, unpacks how this key neurotransmitter affects our mental and physical health. As the brain’s pleasure and reward signal, dopamine is responsible for much of what makes us feel good. However, in today’s world of constant high-reward stimuli, maintaining balance is more difficult than ever. Dr. Lembke explains the delicate pleasure-pain balance that governs dopamine levels and reveals why our culture of indulgence often leads to dopamine deficits.

Dopamine imbalances are exacerbated by modern technology. Dr. Lembke points out how smartphones have become “digital dopamine needles,” delivering endless hits of pleasure, but at a significant cost to our mental well-being. In this episode, she also shares healthy, sustainable ways to boost dopamine, such as engaging in flow states—those moments of deep focus—and building human connections. Additionally, she explains the value of hormetic activities, like cold exposure and intermittent fasting, which naturally stimulate dopamine without causing dependence.


"The smartphone is the modern-day hypodermic needle, delivering digital dopamine 24/7 for a wired generation." - Anna Lembke, MD

Key Takeaways:

  • How dopamine is involved in the pleasure-pain balance
  • The role that serotonin plays in homeostasis
  • Why a world of indulgence has led to dopamine deficits
  • How flow states and human connections stimulate dopamine production
  • Evaluating the risk-reward of psychedelics and dopamine mechanisms
  • Leveraging hormetic activities to boost dopamine levels

Listen now and learn how to maintain balanced dopamine levels in a world of pleasure. Tune in now.


Related Links:
Dr. Anna Lembke's Website
Dr. Anna Lembke's Stanford Profile
Dr. Anna Lembke's Book: Dopamine Nation

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