There’s no safety concern in taking Qualia Focus and Qualia Energy Shot™, though we think of them more as “either/or” rather than “both together” products. Another part of the reason is that both contain caffeine. And, the last part of the reason is that they have an overlap in several other ingredients (e.g., Celastrus, L-theanine, American ginseng).
Taking a full dose of Qualia Focus with Qualia Energy Shot™ would deliver 190 mg of caffeine, which is within the 50-200 mg range where caffeine performs exceptionally well as a nootropic. For people who are not sensitive to this amount of caffeine, there is no reason why Qualia Focus and Qualia Energy Shot™ can’t be used together.