Sabroxy® (Oroxylum indicum bark extract)

Sabroxy® is made from the dried bark of the Indian trumpet tree (Oroxylum indicum), which grows throughout India and Southeast Asia. Its bark has been used for centuries in Ayurveda and other folk traditions, with uses including supporting gastrointestinal function and respiratory health. It is also used as a tonic and is part of popular Ayurvedic herbal tonic blends such as Chyawanprash and Dashamoolarishta. The flavonoids oroxylin A, baicalein, and chrysin are among its main bioactive compounds. Studies with O. indicum extracts and its bioactive compounds have revealed several health-supporting properties, including antioxidant and immunomodulatory benefits that support healthy protection of multiple tissues, including the gastrointestinal tract, liver, cardiovascular system, and brain. Both oroxylin A and baicalein have been shown to cross the blood-brain barrier in preclinical studies. Oroxylin A in particular has been shown to support healthy neuroprotective mechanisms and healthy brain function [1–4].*

TOP BENEFITS OF SABROXY®

Supports healthy brain function*

Supports cognitive health*

QUALIA’S SABROXY® SOURCING

Sabroxy® is prepared from the bark of Oroxylum indicum and standardized for not less than 10% Oroxylin A, 15% Baicalein and 6% Chrysin. To get this high a standardization requires between 50-60 grams of the bark to make 1 gram of the extract (extract ratio 50:1 to 60:1). 

Sabroxy® is non-GMO, gluten-free, vegan, Halal, and Kosher certified.

Sabroxy® is a registered trademark of Sabinsa Corporation.

SABROXY® FORMULATING PRINCIPLES AND RATIONALE

The decision on the amount of Sabroxy to include in a Qualia formula was based on how this extract is most commonly used within the nootropic community. Users typically supplement Sabroxy in amounts ranging from 50 mg to 300 mg, with some of the most experienced users preferring 50-100 mg, especially if it is being supplemented as part of a blend with other nootropic ingredients. We opted to include an amount at the lower end of the range as a complement to the other ingredients in our formula.* 

OROXYLUM INDICUM KEY MECHANISMS

Supports healthy brain function and cognition*

Supports memory performance* [5,6]

Supports cognitive health* [5,7–9]

Support healthy dopamine signaling* [10]

Supports healthy GABA signaling* [8,11]

Supports healthy brain-derived neurotrophic factor (BDNF) levels* [12–16]

Supports healthy neuroprotective functions* [7,8,13,17–21]

Supports healthy hippocampal neurogenesis (animals)* [22]

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

REFERENCES

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