The Ultimate Blend for Brain Health

Sabroxy® (Oroxylum indicum bark extract) is made from the dried bark of the Indian trumpet tree/ (Oroxylum indicum). It supports healthy brain-derived neurotrophic factor (BDNF) function, helping to maintain neurological health and nerve functions. Sabroxy contains a flavonoid called oroxylin-A that supports healthy dopamine signaling which supports motivation and focus.*

Coffeeberry® Whole Coffee Fruit Extract is made from organic coffee fruits; it contains naturally occurring caffeine and polyphenols found in the fruit which promote healthy activity and energy metabolism in the brain. It also indirectly supports the healthy release of neurotransmitters like dopamine and serotonin.*

Cognizin® A clinically studied source of choline (found in various animal products and vegan foods such as nuts and cruciferous vegetables) and cytidine. It supports healthy acetylcholine production, an important neurotransmitter involved in attention, concentration, learning, memory, and neuroplasticity.*

Phosphatidylserine (from sunflower lecithin) is a phospholipid from sunflower lecithin, and brain-essential nutrient. It is a major phospholipid in the brain, supporting healthy membrane and neurotransmitter signaling, especially in parts of the brain related to memory functions.*

Acetyl-L-Carnitine HCl: an acetylated form of L-carnitine. This form of carnitine crosses the blood-brain barrier and is the preferred form for use in brain and nervous system support. It supplies carnitine and acetyl groups that collectively support the healthy production of acetylcholine neurotransmitter molecules, brain energy production, and neuroprotective functions.*

N-Acetyl-L-Tyrosine: N-acetyl-L-tyrosine (NALT) supplies the amino acid L-tyrosine, which is a building block for dopamine and catecholamine neurotransmitter molecules involved in supporting motivation, focus, and executive functions.*

Taurine: one of the most abundant amino acids in the brain and eyes, where it supports brain health, hearing, and vision. It’s involved in promoting long-term potentiation, healthy GABA and glycine neurotransmission, optimal function fo brain-derived neurotrophic factor (BDNF), neuronal mitochondrial function, neuroprotection, and photoreceptor cell visual function.*

L-Theanine: an amino acid found in the leaves used to make green and black teas. It promotes activity in the alpha frequency band; this frequency of brain waves is characteristic of attention and relaxation of the mind without drowsiness. L-theanine promotes focused attention, mental alertness, and calm, relaxed energy.*

L-alpha-Glycerylphosphorylcholine (alpha GPC): a choline form found in the brain. It supports healthy acetylcholine production, an important neurotransmitter involved in attention, concentration, learning, memory, and neuroplasticity. Alpha GPC also supports phospholipid metabolism in the brain, which is important for keeping brain cells healthy.*

Guarana Seed Extract: a caffeine-containing plant native to the Amazon, where it was used to stay awake longer and support brain performance. Similar to other caffeine-containing plants, it promotes optimal activity and energy metabolism in the brain. It also indirectly supports the healthy release of neurotransmitters like dopamine, and serotonin, which are involved in alertness, feelings of energy, mood, and motivation.*

Caffeine (anhydrous): Caffeine is the most widely used nootropic substance in the world. It promotes healthy activity and energy metabolism in the brain and nervous system. It also indirectly supports the healthy release of neurotransmitters like dopamine and serotonin, which are involved in alertness, feelings of energy, mood, and motivation.*

Pyrroloquinoline Quinone disodium: also known as (PQQ) is a vitamin-like antioxidant compound. It supports optimal activity, blood flow, and oxygen metabolism in areas of the prefrontal cortex involved in thinking, attention, and memory. PQQ also supports healthy energy production, mitochondrial health, and cellular protection and repair functions.*

Boron (as boron glycinate): Boron is a trace mineral. It is best known for supporting bone health and optimal sex hormone levels. Studies suggest it may also be a brain-essential nutrient. Adequate dietary intake of boron is needed to support healthy brain electrical activity and cognitive performance, especially in areas related to attention and memory.*

Vitamin C (as ascorbic acid): Vitamin C is a brain-essential nutrient. It’s best known for its neuroprotective support as an antioxidant. Vitamin C is involved in the conversion of dopamine to noradrenaline and helps dampen neuronal over-stimulation by glutamate. It also promotes the regulation of catecholamines and acetylcholine from synaptic vesicles and the formation of myelin.*

Vitamin D3 (as cholecalciferol from VegD3®): VegD3® is Vitamin D3 (cholecalciferol) produced from a non-GMO algal source. Vitamin D3 is a fat-soluble vitamin and a brain essential nutrient involved in the healthy growth and function of neurons by supporting brain‐derived neurotrophic factor (BDNF), glial‐derived neurotrophic factor (GDNF), nerve growth factor (NGF) and other neurotrophic factors. Adequate vitamin D3 is needed for healthy dopamine signaling, neuroprotective functions, and neuroplasticity.*

Thiamine (as thiamine HCl): Thiamine (B1) is a member of the B-complex vitamin family and a brain essential nutrient. It supports healthy brain energy metabolism, neuron health, neurotransmission, and adrenal gland function. Thiamin helps synthesize several neurotransmitters involved in focus, memory, motivation, and mood, including acetylcholine, dopamine, and GABA.*

Riboflavin: Riboflavin (B2) is a member of the B-complex vitamin family and a brain essential nutrient. It supports optimal brain energy production, the production of glutathione (a cellular antioxidant), and healthy adrenal function. Riboflavin is needed for myelin and is used in the metabolism of fats, which is critical in the brain since it is mostly made of fats.*

Niacin (as Niacinamide): Niacinamide (B3) is a member of the B-complex vitamin family and a brain essential nutrient. It supports healthy NAD+ levels, energy production, antioxidant defenses, and cellular repair and stress response functions. Vitamin B3 is critical for maintaining the health of the central nervous system (i.e., it’s neuroprotective).*

Vitamin B6 (as pyridoxal 5'-phosphate): Vitamin B6 is a member of the B-complex vitamin family and a brain essential nutrient. Pyridoxal 5'-phosphate is a coenzyme (i.e., active) form of vitamin B6. It supports the healthy production of brain glucose and energy metabolism. Vitamin B6 is directly or indirectly needed for supporting the production of neurotransmitters related to motivation, focus, and mood, including acetylcholine, dopamine, GABA, and serotonin.*

Folate (as L-5'-methyltetrahydrofolate calcium): Folate (B9) is a member of the B-complex vitamin family and a brain essential nutrient. L-5'-methyltetrahydrofolate calcium is a coenzyme (i.e., active) form of folate. It supports the healthy function of brain and nerve cells, and is needed for the production of myelin. Folate is involved in promoting healthy dopamine, melatonin, noradrenaline, and serotonin, and supports healthy hearing, mood, and vision.*

Vitamin B12 (as methylcobalamin): Vitamin B12 is a B-complex vitamin and a brain essential nutrient. Methylcobalamin is the coenzyme (i.e., active) form of vitamin B12, and the preferred nootropic form. It supports the healthy function of brain and nerve cells, and is needed for the production of myelin. Methylcobalamin is involved in promoting healthyg dopamine, melatonin, noradrenaline, and serotonin, and supports healthy hearing and vision.

Biotin: Biotin (B7) is a B-complex vitamin and a brain essential nutrient. It supports healthy glucose metabolism, which is important because the brain is particularly sensitive to the delivery and metabolism of glucose. Adequate dietary biotin is also important for healthy dopamine neurotransmission.*

Pantothenic Acid (as calcium pantothenate): Pantothenic acid (B5) is a B-complex vitamin and a brain essential nutrient. It supports healthy brain energy production, the synthesis of neurotransmitters (most notably acetylcholine), the production of the myelin required for healthy nerve function, and adrenal function (it’s often referred to as the “anti-stress” vitamin).*

Magnesium (as magnesium aspartate): Magnesium (Mg) is a brain essential mineral. It is needed for the optimal production of dopamine and serotonin, and plays a role in supporting other neurotransmitters, including GABA and glutamate. Mg is also an essential factor in making and activating ATP (brain energy), nerve transmission, blood-brain barrier integrity, a healthy stress response, and hearing and vision.*